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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e489e3e13ca0f590d46e252fcb3de007e9ad648355f3e77c331c02437209c3a0' 
  AND token = 'kIfShq1o/DB5Rf9I3AeI+HhJWxqxl03Oi1CAFwPYZmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}