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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06bb0b4d60e5f4264fc5275c8f55d6b0a809604a324598022ce5d670c82e6aff' 
  AND token = 'GqlLitNA7yA9N5Ep06/I9yaVeaEdcmqf7jiGutXUz2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}