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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68fdc66b790633c612b7044524322d164512e8d14f35eb418b2e51bdb43b66c0' 
  AND token = 'SPJq++RKy2tL9hhb3px+JJNuByXpkk11mfpa5y2rWfU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}