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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f8236461dc411c2e36680bca921729a6a18474d34806f25b609f6f34e1cfe6' 
  AND token = '7B+Itebf/uQy6aSjKDhXNY2225bbajoN6AHHjZ+rM/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}