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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f0f25cb39c69880baedb5c2c76fa4a3c6bb7fd303b1d05b132612da4a973315' 
  AND token = 'enpw1KioWpj67KdKV2J3tkB45QejL5+8tJXmyc61bWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}