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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed5e6a3db9caf85460816a90934d33450e3a3f9d2189e5f2f3aea258d63de87d' 
  AND token = 'I0bAHX8sbS5ZL7eG04cCk1b8Oet28WPfj6h5wCMwZvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}