SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32893f20d834fcc61707e096351a0185d63419b14cfd7febb4ee5a81e795bd7f' 
  AND token = 'YHx5bnzI1yh6TZsCs+4NnyTQeskG8GGpr4AFK/R1HhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}