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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8030d30b32e366469b3256be1366c75cfb07b61f2f33842e2d2d9b5601f3f5b0' 
  AND token = '87GpVA6K+Phd5i3Y1MVqiKu0XbMs3Y48mgNUhaKK0Ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}