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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1122b93715d446cedc3825564a8ab27845a2be5fdc766ed126948bcc352326b' 
  AND token = 'YzIU2aIWzjEFITYPypDBz+afMMXCd6TPYR1qDl6HcVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}