SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ffec8beeafaa936eb95afa0b8b22fb055fa2181fe3f62fc866676b8b9e1457c' 
  AND token = 'QJ/EXUUqgfhOPPCnpgS827EifvwmV/cD43nBdY65gnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}