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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8cf5326bf696f779c88afff874b144b33da28e0aebeeae3823fe2693a8274f2' 
  AND token = 'iT1qevyH2FYuNNYw/IruFAq7Ur8q044TJbGPIiXc1gY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}