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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64b62df5d227d87e7980afdd06fc7e0ec1aa40233420bed41ca1c0c083c4161b' 
  AND token = 'x1RATbDy21LqIqmj4JHYIHzb+hq/YEjUHW9KG9Hp4Mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}