SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8234d932271aa3673526bef4e16408de5c22ebe9115f9e88f2d145af8f26c302' 
  AND token = 'vOR1X7FCEK750nDaPSAj/i9bpNq/hC3y4WIzU8YA7gg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}