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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b6cb1131aef197de539a0e0e158a9736f397c4b1e325272d33ed007bc58b36' 
  AND token = 'Fk9VfOkM+BAy/vzEvl4QOOIGikCsyNKIr3GPc6R/gg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}