SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f2b9a7c02e98f045d20958f7601839c53b7629afd080c68355554b7804ed880' 
  AND token = 'rJ3zcGQB9CB6ktxPc29M9ePeMyDsT/VVHHhnjD4JZjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}