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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccd3f5846c2ca46ff8ba57f83613f5ccb30a73ffa845ea19502c59f0a52c3341' 
  AND token = 'mhne+519ORdkb8fYUOQcI3oT21bQG5yisgNd3+ZoYTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}