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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14275be2c71f86f59127bc306a6a02c69c8b523d87fb11bc33f14d61dd0ca22f' 
  AND token = 'TzaxH6Fga+gElmCHK3DN2MkANEz+IKEmgK+RmcBB8j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}