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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4147d27b74c2db46bc8e1e55ea92f0147b9c8f1bc5ba42c52a15532fa74981cb' 
  AND token = 'U2ZerrHI1qT3NWYwrD4UFmZEsZgtCXndf3ftLiUG66o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}