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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09d16834e0fd0310415b66579bad42954d05a2cade1bd0b4e7b9e6f51068baa8' 
  AND token = 'v4x4XPiOBywYpRrvFG4hPQZ/7W6DKPMpTvQdQdidsr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}