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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65bf4ac83b8e34bdf9794d97560dc40a8a578d16a18eaa446d781cd6be01cbf4' 
  AND token = 'HA2vCWv3vp/1fRDi0j50bj3zjp6d3ZMcZt2SPm/dOvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}