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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c43a3d85ee05f3c64a3d16dd891ec7174a0ece13475b033361bad562d3809cc' 
  AND token = 'fdvQnq41Vwt5RRMOl8XieQVIEsnYoIv9a874Fc/ObQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}