SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c881aeb4a59c451cee9c3f1c1b7e72547717f481bdf123bb46113b41e959786' 
  AND token = 'mJmS1bBVnfKSGhu3MJeQVxIea5Uu1YP+mVfbwsrx8/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}