SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4822fb9aec540d23b7a6b0f2f96e746c7cd348595d75cc961e940bd70610032' 
  AND token = 'qzENpGUg5nKvV0kifmx/44JqilxBXWvifDGh4Hu5RQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}