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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b3d7d1ba8b96e2bb8180153a1f5db868226f1603a9c815e9a52c0174cc51e4' 
  AND token = 'sX+hl5GspbpOEys6NS6TVkRSes44/6xmyzuWeJCsVXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}