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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c8b6687272fe7312955de3aaa2fbefbede25db53679b40cdd2b4d7d5df99ae1' 
  AND token = 'rthJSUrVVNvxndKX/13RVPGoG2WrGrA1joUtNAwAa7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}