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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8caac37a9779edb36d7ee15d0f7964cdd8a5a3f60c7da439cfd796da22aa8e16' 
  AND token = 'T7SOa30Uqm9X+ypiQ8uzlf1CreKAuEeSkUghGmDXdZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}