SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0f90b43cf392aa410794146720fca9c476b1f881dba5d5cba26df189652025' 
  AND token = 'iLHtIdq1mCy2Yo2uLtdOMeXz++Cw6Dsr5zPz3g0Xc8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}