SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3741edfecf937e91ae7eaccd7a7d95488e013d55ca84a1f60dc1e68df8cab549' 
  AND token = 'ElR4WyhXpIFSxCg+/w28aIrXqlsI9yJoadJZsrZ8Kpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}