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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c25c2cd4c3e074bc7c779e515003ec5f069c351e977d9f4b7b3ab94ce086bfcb' 
  AND token = 'K37DHpxaeDzZwRMdb4fPKduqR08M1XeTyK4LFlgCVCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}