SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd707e760b4f6ca25db2aee316736e91be81de6a05b12bdaa661e28e900f7218a' 
  AND token = 'hpxMiekptgRC//1XNNm+1BFp5H0q/tRqbVF53Hr1F3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}