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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44df50b43fc48f90f97e7a6aca01b5a835845f5fe3c90df86cdd5df85d3c22ee' 
  AND token = 'Mtjuhu/yCrXBb2/bZyuxh0UE/Ry+OughNYw9ccFmrDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}