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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78dea4e66da1346d163e87d3932a41837b60183b60f144709176beda9b2fc896' 
  AND token = '4VrOfeYI9wHPzjSX24xtIsB8+GyyQRs9Qg5Uy42Rv5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}