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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4005ced1d9e83a66b335062253129ed164d46a502bb8e256de2e5670e37544f3' 
  AND token = '+1G3IOJcLNp6jwTbIr9YrTHU7vcFLXHY9MvariqWuTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}