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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59325f0948693f49cb7c092016545ec6b915d9aedb5a9122f10ecae9f53f720c' 
  AND token = '59sDYToaWJwpw/J6B2kCGgSrXlr5uF88xj14aCiXAvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}