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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27ef09cc86b40b8ba245e1b46c33e0ab88e61d5a5e8e7dc4e18526ff41246d73' 
  AND token = '2A4CUIkd85AZgsPXaBTFp6+GnCL8/2NF9bDr43djLh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}