SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bf1c2b85990a572a962a6446a2c7800faf59db5839fdea35ea2d4048f2b0cd' 
  AND token = 'A3rh9XTvxL17U0+9kuRWziZ3kyjlYRiNf8zaWvrVtCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}