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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa5b891a8064179324161b7b7f27077df4a243e1b58f6a2ad5cf48ca610f5f5b' 
  AND token = '5PoyGaXuL4RfU5n64nejrLIdmI+7eD2pTbDqz4aQQbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}