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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5a5e8d545d3204092eeabcbb007e44ee3f4ade101aaf5e706f6bf3e573e40a' 
  AND token = 'lV+dj6JRbgxbogX2VEB+hN/2mCWvFgDniQDwxMba70I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}