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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6f43e5d9742827be3f32b912a603671981378a17c0cdb47ec113329499e430' 
  AND token = '62KcIwt1jDjhv3OWMH6EIbqlKcmMIuzdoUmSA52S4OE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}