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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '155a841b2579c4b82f73d583c115eb737789675fdc411234561a93265653cc2d' 
  AND token = 'PwrlhwoMUN6MBmouSCRR1Cw29d3EFFjtVDmjqmF68Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}