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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bf91f32efdeec91a4c80f1d42b628875e704f652d4910170e314f16de94bc76' 
  AND token = 'vzq1ITKtB5zW2qIwlRFN/UveP5rISNuyzZYe5VF5EPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}