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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '727759d4dfcb8881bba91c0af4f12c05411a04db6f69c0974afe49d95e4b119c' 
  AND token = 'B94JgqMLcQ3i0VDy7ABQyxEgREEQ0zkMPibQ9Sf2Ka4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}