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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51fff7b2521add4dbda4214ffca4c8f09f6564bc2fe509be01cc961f798d169f' 
  AND token = '/2I9GiZWQrJcqGMV+kclwAKXHQjtuOwGGkW6b5pBX00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}