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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24892a4c85369a75a39c05b746277f9c9ac3f2cf5783407992e98abe081f7e2f' 
  AND token = 'GUU3NknNRXvYVhfv2qE/WRnfOTWJfkLvo4uSPNSOC9U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}