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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a80e1b6accefc2f5991b0b2e96a28a12ce3932a0d7ebcb05a08c2cd498a198' 
  AND token = 'mf8JNs8CSHVDbTGJm5k9P+ftD6+jnr4onmLX7YMlKHs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}