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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d5a2d83a58a4db78f5333ef54f666f276209fe02848d296c021c2ed3c151ee6' 
  AND token = 'Viu4Oeaq9kV1AzUyDNLra71kOjmY55RHoQEhsiJcQng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}