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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3990f4cc9561c102bf3af84819c899ec5658f422c539b5b3e16fdcf15cf32c63' 
  AND token = 'XJQtERtnyN1iu+hAlkqgP/UosxBv226lRCnL0lyYfvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}