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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b2b00ef226f9e15a2c77a084da54eb0806aa5015ec412bdd2d151f9e954657' 
  AND token = 'TwgBf3hej8NcAMI+d3GxFCCXhjx4sVCs7o20UG5LAls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}