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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ae09a4ba02a0ec1fd0f814ecd8e79cf4e4497f90e1dbfa9639b442425422534' 
  AND token = 'V4t3xY3WrVUkP6YyC4xEfbxV0xUcGalPtyBPSz0mRaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}