SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '270fbe6df88bff3a8eb8cb4c2120acf5b5144132837186ad875b5648c6f2477e' 
  AND token = 'hlkJ814nSdwtIQTii/ocRbuLQ9wxZwSCf2sRpK+cfqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}